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Polyhexamethylene Biguanide (PHMB)

CAS No.: 27083-27-8

Molecular Formula: (C8H18N5Cl)n, n=12-16

Molecular Weight: 2000-2600

Structural Formula:




Poly hexamethylenebiguanide (PHMB) is a new type of green biocide, which is different from the traditional disinfectants such as alcohols (alcohol, etc.), quaternary ammonium salts (benzalkonium chloride, etc.) And chlorine-containing disinfectants (chlorine dioxide, etc). It is colorless, tasteless, safe and non-toxic. Poly hexamethylenebiguanide is suitable for the needs of all kinds of people.

Poly hexamethylene biguanide hydrochloride (PHMB) concentrate is sold as a white to pale yellow solid or as an aqueous solution and used as a preservative or disinfectant. Polyhexamethylene biguanide (PHMB) is an effective public health biocide registered for numerous applications by the U.S. EPA under the Federal Insecticide, Fungicide, and Rodenticide Act, and supported under the Biocidal Products Directive in Europe.

Advantages of Poly hexamethylenebiguanide

  1. Colorless and tasteless, safe and non-toxic, non-flammable, non-explosive, non-corrosive, and non-volatile.
  2. It is easy to dissolve in water and can be prepared by adding water at will according to the required concentration.
  3. The broad-spectrum high-efficiency bactericide has obvious killing effect on common Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and the like.
  4. It is suitable for a wide range of people, from infants to middle-aged and elderly people.
  5. It is suitable for a wide range of scenarios, from public places to household disinfection.


AppearanceColorless or light yellow transparent liquid
Active acid (by titration) %74-78
Refractive Index1.47-1.49
pH(as it)9.0-12.0
Density (25℃, g/cm3)1.15-1.16


Poly hexamethylene biguanide hydrochloride (PHMB) is used as a sanitizer or preservative to kill bacteria and viruses and to control algae in a wide range of applications globally.

As a sanitizer, polyhexamethylene biguanide is used to preserve wet wipes, to control odor in textiles, to prevent microbial contamination in wound irrigation and sterile dressings. This environment-friendly biocide also can be used to disinfect medical/dental utensils and trays, farm equipment, animal drinking water, and hard surfaces for food handling institutions and hospitals; and to deodorize vacuums and toilets.

PHMB biocide is used in antimicrobial hand washes and rubs and air filter treatments as an alternative to ozone. The polyhexamethylene biguanide (PHMB) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.

As a preservative, PHMB is used in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.

Package and Storage

Packed in 25kg net in a plastic drum. Sealed storage at room temperature, away from direct sunlight.


Polyhexamethylene Biguanidine Hydrochloride; Guanidine; Poly(hexamethylene Diguanide) Hydrochloride.

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